Erratum to Issaenko OA, et al. Cell Cycle Volume 11, Issue 9; pp. 1804-17

This article refers to:

Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes

Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes

Olga A. Issaenko and Alexander Yu Amerik, authors of the recently published paper, "Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes" wish to make the following clarifications regarding compound names referenced therein.

1. The authors note that on pages 1809 and 1810, the label and the legend for Figure 4B appeared incorrectly in part. Compound name “KVI-14” should instead read “RA-14.”

2. The authors note that small molecule inhibitor RA-9 used in this study is structurally different from another chalcone-derivative “compound 10 RA-9” referenced in 1. To avoid further confusion, in Table 1 below, authors provide chemical formulas, other known names and known references for chalcone-derivatives used in this study.

Table 1. Chemical formulas, other known names and known references for chalcone-derivatives.

Table

Compound	R1	R2	P	Reported IC50 (µM) HeLa cells	Alternative nomenclature	Reference
RA-1	Cl	Cl	-CO-Phenylalanine	0.32		1
AM146	H	Cl	CH3	1.5–1.83	RAMB1	2, 3
RA-9	H	NO2	H	2.37	RAMB9	2
RA-14	H	NO2	CH3	2.03	KVI-14, RAMB14	2

Acknowledgment

Proprietary rights and synthesis of compounds: inquiries to Saeed R. Khan, The John Hopkins University, Baltimore, Maryland 21231; E-mail: [email protected].