Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis

Julia Seiderer Department of Internal Medicine II, University of Munich, Germany

Fabian Schnitzler Department of Internal Medicine II, University of Munich, Germany; Department of Clinical Chemistry, University of Munich, Germany

Stephan Brand Department of Internal Medicine II, University of Munich, GermanyCorrespondence[email protected]

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Tanja Staudinger Department of Internal Medicine II, University of Munich, Germany

Simone Pfennig Department of Internal Medicine II, University of Munich, Germany

Karin Herrmann Department of Radiology – Grosshadern, University of Munich, Germany

Katrin Hofbauer Department of Internal Medicine II, University of Munich, Germany

Julia Dambacher Department of Internal Medicine II, University of Munich, Germany

Cornelia Tillack Department of Internal Medicine II, University of Munich, Germany

Michael Sackmann Department of Internal Medicine II, University of Munich, Germany; Department of Internal Medicine II, Hospital Bamberg, Germany

Burkhard Göke Department of Internal Medicine II, University of Munich, Germany

Peter Lohse Department of Clinical Chemistry, University of Munich, Germany

Thomas Ochsenkühn Department of Internal Medicine II, University of Munich, Germany

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