Identification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes

A. Nakashima Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, JapanCorrespondence[email protected]

H. Kawashita Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, Japan

N. Masuda Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, Japan

C. Saxer Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, Japan

M. Niina Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, Japan

Y. Nagae Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, Japan

K. Iwasaki Preclinical Development Department, Tsukuba Research Institute, Novartis Pharma K. K., Ibaraki, Japan

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