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Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 12
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Original Article

Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies

J. R. Kenny AstraZeneca R&D Charnwood, Loughborough, UK
,
L. Chen Tissue Engineering Group, School of Pharmaceutical Sciences, University of Nottingham, Nottingham, UK
,
D. F. McGinnity AstraZeneca R&D Charnwood, Loughborough, UKCorrespondence[email protected]
,
K. Grime AstraZeneca R&D Charnwood, Loughborough, UK
,
K. M. Shakesheff Tissue Engineering Group, School of Pharmaceutical Sciences, University of Nottingham, Nottingham, UK
,
B. Thomson Tissue Engineering Group, School of Pharmaceutical Sciences, University of Nottingham, Nottingham, UK
&
R. Riley AstraZeneca R&D Charnwood, Loughborough, UK
 show all
Pages 1500-1517 | Received 23 Apr 2008, Accepted 22 Sep 2008, Published online: 21 Nov 2008

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