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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 6
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Research Article

Cocktail-substrate assay system for mechanism-based inhibition of CYP2C9, CYP2D6, and CYP3A using human liver microsomes at an early stage of drug development

K. MoriDrug Metabolism and Pharmacokinetic Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Toda, Japan
,
H. HashimotoDrug Metabolism and Pharmacokinetic Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Toda, Japan
,
H. TakatsuDrug Metabolism and Pharmacokinetic Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Toda, Japan
,
M. Tsuda-TsukimotoDrug Metabolism and Pharmacokinetic Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Toda, Japan
&
T. KumeDrug Metabolism and Pharmacokinetic Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Toda, JapanCorrespondence[email protected]
Pages 415-422 | Received 27 Dec 2008, Accepted 13 Feb 2009, Published online: 01 Jun 2009

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