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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 10
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Research Article

Metabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate

M. FonsiDepartments of DMPK, IRBM, Merck Research Laboratories, Rome, ItalyCorrespondence[email protected]
,
F. FioreDepartments of Pharmacology, IRBM, Merck Research Laboratories, Rome, Italy
,
P. JonesDepartments of Chemistry, IRBM, Merck Research Laboratories, Rome, Italy
,
O. KinzelDepartments of Chemistry, IRBM, Merck Research Laboratories, Rome, Italy
,
R. LauferDepartments of Pharmacology, IRBM, Merck Research Laboratories, Rome, Italy
,
M. RowleyDepartments of Chemistry, IRBM, Merck Research Laboratories, Rome, Italy
&
E. MonteagudoDepartments of DMPK, IRBM, Merck Research Laboratories, Rome, Italy
 show all
Pages 722-737 | Received 14 Apr 2009, Accepted 01 Jun 2009, Published online: 01 Jul 2009

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