Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA

Poonam GiriDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and

Prashant DelvadiaDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and

Laxmikant GuptaDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and

Nirmal PatelDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and

Priyal TrivediDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and

Krishna LadDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and

Hiren M. PatelDepartment of Molecular Pharmacology, Zydus Research Centre, Ahmedabad, India

Nuggehally R. SrinivasDepartment of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Ahmedabad, India and Correspondence[email protected]

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