General Xenobiochemistry
A novel Css-MRTpo approach to simulate oral plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite in humans using chimeric mice with humanized livers
Hidetaka KamimuraLaboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, JapanCorrespondence[email protected]
http://orcid.org/0000-0002-8371-7159
http://orcid.org/0000-0002-8371-7159, Shotaro UeharaLaboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, Japanhttp://orcid.org/0000-0002-1359-8828
http://orcid.org/0000-0002-1359-8828 & Hiroshi SuemizuLaboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, Japanhttp://orcid.org/0000-0002-3706-2454
http://orcid.org/0000-0002-3706-2454