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Xenobiotica

the fate of foreign compounds in biological systems

Volume 52, 2022 - Issue 7

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Animal Pharmacokinetics and Metabolism

Elucidation of clearance mechanism of TP0463518, a novel hypoxia-inducible factor prolyl hydroxylase inhibitor: does a species difference in excretion routes exist between humans and animals?

Hiroki TakanoDrug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, JapanCorrespondence[email protected]

Akiko Mizuno-YasuhiraDrug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, Japan

Jun-ichi YamaguchiDrug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, Japan

Hiromi EndoDrug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, Japan

Pages 729-741 | Received 31 Aug 2022, Accepted 09 Nov 2022, Published online: 17 Nov 2022

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https://doi.org/10.1080/00498254.2022.2147038
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