Identification of the Fluvirucin B₂ (Sch 38518) Biosynthetic Gene Cluster from Actinomadura fulva subsp. indica ATCC 53714: substrate Specificity of the β-Amino Acid Selective Adenylating Enzyme FlvNFootnote
Abbreviations: 3-MeAsp, 3-methylaspartate; ACP, acyl carrier protein; PKS, polyketide synthase; MESG, 2-amino-6-mercapto-7-methylpurine ribonucleoside; dTDP, thymidine diphosphate.

Akimasa MiyanagaDepartment of Chemistry, Tokyo Institute of Technology, Tokyo, Japan

Yuki HayakawaDepartment of Chemistry and Materials Science, Tokyo Institute of Technology, Tokyo, Japan

Mario NumakuraDepartment of Chemistry, Tokyo Institute of Technology, Tokyo, Japan

Junko HashimotoJapan Biological Informatics Consortium, Tokyo, Japan

Kuniko TeruyaOkinawa Biotechnology Business Support Center, Okinawa Institute of Advanced Sciences, Uruma, Japan

Takashi HiranoOkinawa Biotechnology Business Support Center, Okinawa Institute of Advanced Sciences, Uruma, Japan;Okinawa Biotechnology Business Support Center, Okinawa Science and Technology Promotion Center, Uruma, Japan

Kazuo Shin-yaNational Institute of Advanced Industrial Science and Technology, Tokyo, Japan

Fumitaka KudoDepartment of Chemistry, Tokyo Institute of Technology, Tokyo, Japan

Tadashi EguchiDepartment of Chemistry and Materials Science, Tokyo Institute of Technology, Tokyo, JapanCorrespondence[email protected]

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