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Journal of Biopharmaceutical Statistics Volume 22, 2012 - Issue 4: Adaptive Designs for Clinical Trials: Considerations about and Beyond the FDA Adaptive Designs Guidance
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Original Articles

Flexible Analytical Methods for Adding a Treatment Arm Mid-Study to an Ongoing Clinical Trial

Jordan J. Elm Medical University of South Carolina, Charleston, South Carolina, USACorrespondence[email protected]
,
Yuko Y. Palesch Medical University of South Carolina, Charleston, South Carolina, USA
,
Gary G. Koch University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
,
Vanessa Hinson Medical University of South Carolina, Charleston, South Carolina, USA
,
Bernard Ravina University of Rochester, Rochester, New York, USA
&
Wenle Zhao Medical University of South Carolina, Charleston, South Carolina, USA
Pages 758-772 | Received 22 Jan 2010, Accepted 10 Sep 2010, Published online: 31 May 2012

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