Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches

Vieri Piazzini1 Department of Chemistry, University of Florence, Sesto Fiorentino, FI, Italy and

Elena Monteforte1 Department of Chemistry, University of Florence, Sesto Fiorentino, FI, Italy and

Cristina Luceri2 NEUROFARBA, Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy

Elisabetta Bigagli2 NEUROFARBA, Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy

Anna Rita Bilia1 Department of Chemistry, University of Florence, Sesto Fiorentino, FI, Italy and

Maria Camilla Bergonzi1 Department of Chemistry, University of Florence, Sesto Fiorentino, FI, Italy and Correspondence[email protected]

Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches

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Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches

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