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Journal of Chemotherapy Volume 34, 2022 - Issue 6

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Anticancer Original Research Papers

High dose methotrexate in adult Egyptian patients with hematological malignancies: impact of ABCB1 3435C > T rs1045642 and MTHFR 677C > T rs1801133 polymorphisms on toxicities and delayed elimination

Abdel-Hameed I. M. Ebida Department of Pharmacy Practice, Faculty of Pharmacy, Helwan University, Cairo, Egypt

Ahmed Hossama Department of Pharmacy Practice, Faculty of Pharmacy, Helwan University, Cairo, EgyptCorrespondence[email protected]

https://orcid.org/0000-0003-3456-9695

Mosaad M. El Gammalb Medical Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt

Sameh Sororc Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Cairo, Egypt

Nadia O.M Mangoudc Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Cairo, Egypt

Mohamed Adel Mahmouda Department of Pharmacy Practice, Faculty of Pharmacy, Helwan University, Cairo, Egypt

Pages 381-390 | Received 08 May 2021, Accepted 17 Nov 2021, Published online: 13 Dec 2021

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https://doi.org/10.1080/1120009X.2021.2009723
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