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Amyloid
The Journal of Protein Folding Disorders
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Research Article

Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis

Janett Köppena Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), GermanyView further author information
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Martin Kleinschmidta Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), GermanyView further author information
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Markus Morawskib Paul Flechsig Institute – Center of Neuropathology and Brain Research, Leipzig, GermanyView further author information
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Jens-Ulrich Rahfelda Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), GermanyView further author information
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Michael Wermanna Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), GermanyView further author information
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Holger Cynisa Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Germany;f Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), GermanyView further author information
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Ute Hegenbartc Department of Hematology, Oncology and Rheumatology, Amyloidosis Center, University Hospital, Heidelberg, GermanyView further author information
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Christoph Danield Department of Nephropathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, GermanyView further author information
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Steffen Roßnerb Paul Flechsig Institute – Center of Neuropathology and Brain Research, Leipzig, GermanyView further author information
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Stephan Schillinga Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Germany;e Faculty of Applied Biosciences and Bioprocess Technology, Anhalt University of Applied Sciences, Köthen, GermanyCorrespondence[email protected]
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Anja Schulzea Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Germany;e Faculty of Applied Biosciences and Bioprocess Technology, Anhalt University of Applied Sciences, Köthen, GermanyCorrespondence[email protected]
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Received 25 Oct 2023, Accepted 15 May 2024, Published online: 27 May 2024

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