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Expert Opinion on Investigational Drugs Volume 32, 2023 - Issue 2
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Original Research

Pharmacokinetics, pharmacodynamics, safety, and immunogenicity of Gerilimzumab (GB224), a recombinant humanized interleukin-6 monoclonal antibody, in healthy Chinese adults: A randomized controlled dose–escalation study

Diqin Yana Clinical Trial Institution, Peking University People’s Hospital, Beijing, China;b Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, ChinaView further author information
,
Suping Niua Clinical Trial Institution, Peking University People’s Hospital, Beijing, ChinaView further author information
,
Dingyuan Hua Clinical Trial Institution, Peking University People’s Hospital, Beijing, China;b Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, ChinaView further author information
,
Wenliang Donga Clinical Trial Institution, Peking University People’s Hospital, Beijing, China;b Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, ChinaView further author information
,
Yunjuan Sunc Beijing United-Power Pharma Tech Co., Ltd, Beijing, ChinaView further author information
,
Qian Wanga Clinical Trial Institution, Peking University People’s Hospital, Beijing, ChinaView further author information
,
Simin Wanga Clinical Trial Institution, Peking University People’s Hospital, Beijing, China;d Department of Clinical Pharmacy, Xuzhou Medical University, Xuzhou, ChinaView further author information
,
Qun Gua Clinical Trial Institution, Peking University People’s Hospital, Beijing, ChinaView further author information
,
Gang Liue Department of Pharmacy, Peking University People’s Hospital, Beijing, ChinaView further author information
,
Jiaxue Wangf Department of Pharmacy, Guizhou Provincial People’s Hospital, Guiyang, ChinaORCID Iconhttps://orcid.org/0000-0002-9789-034XView further author information
ORCID Icon,
Liming Chena Clinical Trial Institution, Peking University People’s Hospital, Beijing, ChinaView further author information
,
Jie Lvg Department of Intensive Care Units, Peking University People’s Hospital, Beijing, ChinaView further author information
,
Qingshan Zhengh The Center for Drug Clinical Research of Shanghai University of TCM, Shanghai, ChinaView further author information
,
Haifeng Songi State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, ChinaCorrespondence[email protected]
View further author information
&
Yi Fanga Clinical Trial Institution, Peking University People’s Hospital, Beijing, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3547-5829View further author information
ORCID Icon show all
Pages 161-170 | Received 20 Oct 2022, Accepted 07 Feb 2023, Published online: 20 Feb 2023

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