Envisioning the development of a CRISPR-Cas mediated base editing strategy for a patient with a novel pathogenic CRB1 single nucleotide variant

J.-S. Bellingratha Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;b Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UKView further author information

M. E. McClementsa Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;b Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UKView further author information

M. Shanksc Genetics Laboratories, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UKView further author information

P. Cloustonc Genetics Laboratories, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UKView further author information

M. D. Fischera Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;b Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UKView further author information

R. E. MacLarena Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;b Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UKCorrespondence[email protected]
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Envisioning the development of a CRISPR-Cas mediated base editing strategy for a patient with a novel pathogenic CRB1 single nucleotide variant

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Envisioning the development of a CRISPR-Cas mediated base editing strategy for a patient with a novel pathogenic CRB1 single nucleotide variant

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