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Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors
Minhang XinDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Weiming DuanDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Yifan FengDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Yuan-Yuan HeiDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Hao ZhangDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Ying ShenDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Hong-Yi ZhaoDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
, Shuai MaoDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaView further author information
& San-Qi ZhangDepartment of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. ChinaCorrespondence[email protected]
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Pages 651-656
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Received 05 Jan 2018, Accepted 20 Feb 2018, Published online: 14 Mar 2018
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