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Research Paper
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
David Malinaka Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic;b Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech RepublicCorrespondence[email protected]
https://orcid.org/0000-0002-0665-0667View further author information
Rafael Dolezala Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic;b Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
https://orcid.org/0000-0002-9891-9829View further author information
Vendula Hepnarovab Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic;c Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
https://orcid.org/0000-0002-6445-2669View further author information
Miroslava Hozovab Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech RepublicView further author information
, Rudolf Andrysa Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic
https://orcid.org/0000-0003-1108-3924View further author information
Petr Bzoneka Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic;c Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech RepublicView further author information
, Veronika Racakovad Faculty of Informatics and Management, Center for Basic and Applied Research, University of Hradec Kralove, Hradec Kralove, Czech RepublicView further author information
, Jan Korabecnyb Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic;c Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
https://orcid.org/0000-0001-6977-7596View further author information
Lukas Goreckib Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
https://orcid.org/0000-0002-4791-6556View further author information
Eva Mezeiovab Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
https://orcid.org/0000-0002-9986-5017View further author information
Miroslav Psotkaa Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic;b Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
https://orcid.org/0000-0002-7857-7411View further author information
Daniel Junb Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic;c Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
https://orcid.org/0000-0002-0882-6304View further author information
Kamil Kucaa Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic;b Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
https://orcid.org/0000-0001-9664-1109View further author information
Kamil Musileka Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic;b Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech RepublicCorrespondence[email protected]
https://orcid.org/0000-0002-7504-4062View further author information
Pages 478-488
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Received 01 Jul 2019, Accepted 24 Dec 2019, Published online: 07 Jan 2020
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