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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 35, 2020 - Issue 1
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Research Paper

Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and insilico studies

Ismail M. M. Othmana Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut, EgyptORCID Iconhttps://orcid.org/0000-0002-8549-4016View further author information
ORCID Icon,
Mohamed A. M. Gad-Elkareema Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut, Egypt;b Department of Chemistry, Faculty of Science and Arts of Baljurashi, Albaha University, Saudi ArabiaView further author information
,
Abd El-Galil E. Amrc Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;d Applied Organic Chemistry Department, National Research Centre, Giza, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1338-706XView further author information
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Mohamed A. Al-Omarc Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaView further author information
,
Eman S. Nossiere Pharmaceutical Medicinal Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, EgyptView further author information
&
Elsayed A. Elsayedf Zoology Department, Bioproducts Research Chair, Faculty of Science, King Saud University, Riyadh, Saudi Arabia;;g Chemistry of Natural and Microbial Products Department, National Research Centre, Cairo, EgyptView further author information
Pages 1491-1502 | Received 28 May 2020, Accepted 22 Jun 2020, Published online: 16 Jul 2020

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