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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 35, 2020 - Issue 1
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Design, synthesis and biological evaluation of novel tetrahydrothieno [2,3-c]pyridine substitued benzoyl thiourea derivatives as PAK1 inhibitors in triple negative breast cancer

Dahong Yaoa School of Pharmaceutical Sciences, Shenzhen Technology University, Shenzhen, China;b School of Pharmaceutical Sciences, Guangdong Key Laboratory for Genome Stability and Human Disease Prevention, Shenzhen University Health Science Center, Shenzhen University, Shenzhen, ChinaView further author information
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Jian Huangc Drug Development Department, Shenzhen Honghui Bio-Pharmaceutical Co. Ltd., Shenzhen, ChinaView further author information
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Jinhui Wangc Drug Development Department, Shenzhen Honghui Bio-Pharmaceutical Co. Ltd., Shenzhen, ChinaView further author information
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Zhendan Hea School of Pharmaceutical Sciences, Shenzhen Technology University, Shenzhen, China;b School of Pharmaceutical Sciences, Guangdong Key Laboratory for Genome Stability and Human Disease Prevention, Shenzhen University Health Science Center, Shenzhen University, Shenzhen, ChinaCorrespondence[email protected]
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&
Jin Zhanga School of Pharmaceutical Sciences, Shenzhen Technology University, Shenzhen, China;d Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, ChinaCorrespondence[email protected]
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Pages 1524-1538 | Received 02 Mar 2020, Accepted 10 Jul 2020, Published online: 04 Aug 2020

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