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Research Paper
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H
Graziella Toccoa Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, ItalyCorrespondence[email protected]
https://orcid.org/0000-0003-0081-5704View further author information
, https://orcid.org/0000-0003-0081-5704View further author information
Francesca Espositoa Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, Italyhttps://orcid.org/0000-0001-9725-7977View further author information
, Pierluigi Cabonia Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, Italyhttps://orcid.org/0000-0003-2448-3767View further author information
, Antonio Lausa Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, ItalyView further author information
, John A. Beutlerb Molecular Targets Program, National Cancer Institute, Frederick, MD, USAhttps://orcid.org/0000-0002-4646-1924View further author information
, Jennifer A. Wilsonb Molecular Targets Program, National Cancer Institute, Frederick, MD, USAView further author information
, Angela Coronaa Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, Italyhttps://orcid.org/0000-0002-6630-8636View further author information
, Stuart F. J. Le Gricec Basic Research Laboratory, National Cancer Institute, Frederick, MD, USAhttps://orcid.org/0000-0001-5818-8796View further author information
& Enzo Tramontanoa Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, Italyhttps://orcid.org/0000-0002-4849-0980View further author information
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Pages 1953-1963
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Received 20 Aug 2020, Accepted 08 Oct 2020, Published online: 03 Nov 2020
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