Cancer Biology & Therapy
Volume 22, 2021 - Issue 10-12
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Research Paper
Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo
Aakash V. Jhaveria Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);b Master of Science in Biotechnology Program, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US)View further author information
, Lanlan Zhoua Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);c Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);d Brown University and the Lifespan Health System, Providence, Ri, United States (US);e Cancer Center at Brown University, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US)View further author information
, Marie D. Ralfff MD/PhD Program, The Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States (US)
https://orcid.org/0000-0003-2113-0974View further author information
Young S. Leea Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);d Brown University and the Lifespan Health System, Providence, Ri, United States (US);e Cancer Center at Brown University, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US)View further author information
, Arunasalam Navaraja Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);c Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);d Brown University and the Lifespan Health System, Providence, Ri, United States (US);e Cancer Center at Brown University, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US)View further author information
, Benedito A. Carneirod Brown University and the Lifespan Health System, Providence, Ri, United States (US);e Cancer Center at Brown University, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US);g Brown University and the Lifespan Cancer Institute, Providence, Ri, United States (US)View further author information
, Howard Safrand Brown University and the Lifespan Health System, Providence, Ri, United States (US);e Cancer Center at Brown University, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US);g Brown University and the Lifespan Cancer Institute, Providence, Ri, United States (US)View further author information
, Varun V. Prabhuh Oncoceutics, Inc, Philadelphia, Pa, United States (US)View further author information
, Eric A. Rossi Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, United States (US)View further author information
, Seulki Leej Theraly Pharmaceutics, Inc, Baltimore, MD, United States (US)View further author information
& Wafik S. El-Deirya Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);b Master of Science in Biotechnology Program, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US);c Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University, Providence, RI, United States (US);d Brown University and the Lifespan Health System, Providence, Ri, United States (US);e Cancer Center at Brown University, the Warren Alpert Medical School, Brown University, Providence, Ri, United States (US);g Brown University and the Lifespan Cancer Institute, Providence, Ri, United States (US)Correspondence[email protected]
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Pages 607-618
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Received 01 Jun 2021, Accepted 09 Aug 2021, Published online: 02 Dec 2021
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