BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes

Li Maa Department of Hematology, Children’s Hospital of Soochow University, Suzhou, China;b Department of Pediatrics, The Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, Huaian, ChinaView further author information

Jianwei Wangc Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Yongping Zhanga Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Fang Fangc Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Jing Linga Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Xinran Chua Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Zimu Zhangc Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Yanfang Taoc Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Xiaolu Lic Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Yuanyuan Tianc Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, China;a Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Zhiheng Lia Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Xu Sanga Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Kunlong Zhanga Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Lihui Lua Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Xiaomei Wana Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Yanling Chena Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Juanjuan Yua Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Ran Zhuoa Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Shuiyan Wud Intensive Care Unit, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Jun Lua Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaView further author information

Jian Panc Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou, China

https://orcid.org/0000-0002-0292-5141 View further author information

Shaoyan Hua Department of Hematology, Children’s Hospital of Soochow University, Suzhou, ChinaCorrespondence[email protected]
[email protected]
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BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes

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BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes

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