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Autophagy Volume 17, 2021 - Issue 10
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Research Paper - Translational

PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1)

Peihua Luoa Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Hao Yana Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Jiangxia Dua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Xueqin Chenb Department of Oncology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People´s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaView further author information
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Jinjin Shaoa Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Ying Zhanga Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Zhifei Xua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Ying Jina Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaView further author information
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Nengming Linc Laboratory of Clinical Pharmacology, Affiliated Hangzhou First People´s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaView further author information
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Bo Yanga Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaCorrespondence[email protected]
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&
Qiaojun Hea Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaCorrespondence[email protected]
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Pages 3221-3237 | Received 07 Apr 2020, Accepted 10 Nov 2020, Published online: 14 Dec 2020

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