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Epigenetics Volume 11, 2016 - Issue 10
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Research Paper

Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma

Simone JueligerAstex Pharmaceuticals, Cambridge, UK
,
John LyonsAstex Pharmaceuticals, Cambridge, UK
,
Sara CannitoGastroenterology Unit, IRCCS “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Italy;Institute for Liver and Digestive Health, University College London (UCL), Royal Free Hospital, London, UK
,
Illar PataDepartment of Gene Technology, Tallinn University of Technology (TTU), IVEX Lab, Tallinn, Estonia
,
Pille PataDepartment of Gene Technology, Tallinn University of Technology (TTU), IVEX Lab, Tallinn, Estonia
,
Marianna ShkolnayaDepartment of Gene Technology, Tallinn University of Technology (TTU), IVEX Lab, Tallinn, Estonia
,
Oriana Lo ReCenter for Translational Medicine (CTM), International Clinical Research Center (ICRC), St. Anne's University Hospital, Brno, Czech Republic
,
Marion PeyrouDepartament de Bioquímica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain
,
Francesc VillarroyaDepartament de Bioquímica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain
,
Valerio PazienzaGastroenterology Unit, IRCCS “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Italy
,
Francesca RappaDepartment of Experimental Biomedicine and Clinical Neurosciences, Section of Human Anatomy, University of Palermo, Palermo, Italy;Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
,
Francesco CappelloDepartment of Experimental Biomedicine and Clinical Neurosciences, Section of Human Anatomy, University of Palermo, Palermo, Italy;Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
,
Mohammad AzabAstex Pharmaceuticals, Pleasanton, CA, USA
,
Pietro TavernaAstex Pharmaceuticals, Pleasanton, CA, USA
&
Manlio VinciguerraGastroenterology Unit, IRCCS “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Italy;Institute for Liver and Digestive Health, University College London (UCL), Royal Free Hospital, London, UK;Center for Translational Medicine (CTM), International Clinical Research Center (ICRC), St. Anne's University Hospital, Brno, Czech Republic;Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, ItalyCorrespondence[email protected]
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Pages 709-720 | Received 11 May 2016, Accepted 13 Jul 2016, Published online: 20 Sep 2016

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