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Research Article

Bioanalysis of free antisense oligonucleotide payload from antibody–oligonucleotide conjugate by hybridization LC-MS/MS

Di Jianga Drug Metabolism & Pharmacokinetics, Biogen, 225 Binney St, Cambridge, MA02142, USA;b Current address: Denali Therapeutics, 161 Oyster Point Blvd., South San Francisco, CA94080, USAORCID Iconhttps://orcid.org/0000-0001-9795-6831
ORCID Icon,
Pei Lia Drug Metabolism & Pharmacokinetics, Biogen, 225 Binney St, Cambridge, MA02142, USA;c Current address: Vertex Pharmaceuticals, 50 Northern Avenue, Boston, MA02210, USA
&
Long Yuana Drug Metabolism & Pharmacokinetics, Biogen, 225 Binney St, Cambridge, MA02142, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1863-2308
ORCID Icon
Received 21 Apr 2024, Accepted 06 Jun 2024, Published online: 23 Jul 2024

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