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mAbs Volume 13, 2021 - Issue 1
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The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearance

Eugenia Opolka-Hoffmanna Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, GermanyView further author information
,
Gregor Jordana Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, GermanyView further author information
,
Michael Ottenederb Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Basel, SwitzerlandView further author information
,
Robin Kieferlea Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, GermanyView further author information
,
Martin Lechmanna Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, GermanyView further author information
,
Gerhard Winterc Department of Pharmacy, Pharmaceutical Technology & Biopharmaceutics, Ludwig-Maximilians-University, Munich, GermanyView further author information
&
Roland F. Staacka Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, GermanyCorrespondence[email protected]
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Article: 1995929 | Received 09 Aug 2021, Accepted 15 Oct 2021, Published online: 11 Nov 2021

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