Reduction of monoclonal antibody viscosity using interpretable machine learning

Emily K. Makowskia Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA;b Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USAView further author information

Hsin-Ting Chenb Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USAView further author information

Tiexin Wangb Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USAView further author information

Lina Wub Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USAView further author information

Jie Huanga Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA;b Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USAView further author information

Marissa Mockd Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USAView further author information

Patrick Underhille Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USAView further author information

Emma Pelegri-O’Dayd Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USAView further author information

Erick Maglalangf Drug Product Technologies, Amgen Inc, Thousand Oaks, CA, USAView further author information

Dwight Wintersd Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USAView further author information

Peter M. Tessiera Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA;b Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA;g Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USACorrespondence[email protected]

https://orcid.org/0000-0002-3220-007X View further author information

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Reduction of monoclonal antibody viscosity using interpretable machine learning

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