Potential binding modes of the gut bacterial metabolite, 5-hydroxyindole, to the intestinal L-type calcium channels and its impact on the microbiota in rats

Barbora Waclawikováa Host-Microbe Metabolic Interactions, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The NetherlandsView further author information

Paulo Cesar Telles de Souzab Molecular Microbiology and Structural Biochemistry (MMSB - UMR 5086), CNRS & University of Lyon, Lyon, FranceView further author information

Markus Schwalbea Host-Microbe Metabolic Interactions, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The NetherlandsView further author information

Constantinos G. Neochoritisc Department of Chemistry, University of Crete, Heraklion, GreeceView further author information

Warner Hoornenborgd Department of Behavioral Neurosciences, Cluster Neurobiology, Groningen Institute of for Evolutionary Life Sciences (GELIFES), University of Groningen, Groningen, The NetherlandsView further author information

Sieger A. Nelemanse Department of Molecular Neurobiology, Groningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen, Groningen, The NetherlandsView further author information

Siewert J. Marrinkf Molecular Dynamics, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen, The NetherlandsView further author information

Sahar El Aidya Host-Microbe Metabolic Interactions, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The NetherlandsCorrespondence[email protected]