Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

Kenneth W. WitwerDepartment of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA;Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Bas W.M. Van BalkomDivision Internal Medicine and Dermatology, Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands

Stefania BrunoDepartment of Medical Sciences and Molecular Biotechnology Center, University of Torino, Torino, Italy

Andre ChooBioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore

Massimo DominiciMAB Laboratory, TPM of Mirandola, Mirandola, Italy;Division of Oncology, University of Modena and Reggio Emilia, Modena, Italy

Mario GimonaGMP Laboratory, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Research Program Nanovesicular Therapies, Department of Transfusion Medicine and Celericon Therapeutics G.m.b.H., Paracelsus Medical University (PMU), Salzburg, Austria

Andrew F. HillDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Australia

https://orcid.org/0000-0001-5581-2354

Dominique De KleijnDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands

Mickey KohDepartment of Haematology, St George’s University Hospital NHS Trust, London, UK;Cell Therapy Facility, Blood Services Group Health Sciences Authority, Singapore, Singapore

Ruenn Chai LaiInstitute of Medical Biology, Agency for Science, Technology and Research, Singapore, Singapore

S. Alex MitsialisDepartment of Pediatrics, Harvard Medical School & Division of Newborn Medicine, Boston Children’s Hospital, Boston, MA, USA

Luis A. OrtizDivision of Environmental and Occupational Medicine, Department of Environmental and Occupational Health, Graduate School of Public Health at the University of Pittsburgh, Pittsburgh, PA, USA

Eva RohdeGMP Laboratory, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Research Program Nanovesicular Therapies, Department of Transfusion Medicine and Celericon Therapeutics G.m.b.H., Paracelsus Medical University (PMU), Salzburg, Austria

Takashi AsadaDepartment of Tissue Regeneration Science and Engineering, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

Wei Seong TohFaculty of Dentistry, National University of Singapore, Singapore, Singapore

Daniel J. WeissHealth Sciences Research Facility, University of Vermont College of Medicine, Burlington, VT, USA

Lei ZhengDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China

Bernd GiebelInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyCorrespondence[email protected]

Sai Kiang LimInstitute of Medical Biology, Agency for Science, Technology and Research, Singapore, Singapore;Department of Surgery, YLL School of Medicine, National University of Singapore, Singapore, SingaporeCorrespondence[email protected]

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Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

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