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OncoImmunology Volume 10, 2021 - Issue 1
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Original Research

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

Sarah Bontea Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium;b Cancer Research Institute Ghent (CRIG), Ghent, BelgiumORCID Iconhttps://orcid.org/0000-0002-0637-4893View further author information
ORCID Icon,
Stijn de Munterb Cancer Research Institute Ghent (CRIG), Ghent, Belgium;c Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Lore Billietc Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Glenn Goetgelukb Cancer Research Institute Ghent (CRIG), Ghent, Belgium;c Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Joline Ingelsc Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Hanne Jansenc Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Melissa Pillec Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Laurenz de Cockb Cancer Research Institute Ghent (CRIG), Ghent, Belgium;d Department of Biomolecular Medicine, Ghent University, Ghent, BelgiumView further author information
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Karin Weeningc Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Tom Taghonb Cancer Research Institute Ghent (CRIG), Ghent, Belgium;c Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Georges Leclercqb Cancer Research Institute Ghent (CRIG), Ghent, Belgium;c Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Bart Vandekerckhoveb Cancer Research Institute Ghent (CRIG), Ghent, Belgium;c Department of Diagnostic Sciences, Ghent University, Ghent, BelgiumView further author information
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Tessa Kerrea Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium;b Cancer Research Institute Ghent (CRIG), Ghent, Belgium;c Department of Diagnostic Sciences, Ghent University, Ghent, Belgium;e Department of Hematology, Ghent University Hospital, Ghent, BelgiumCorrespondence[email protected]
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Article: 1954800 | Received 12 Apr 2021, Accepted 08 Jul 2021, Published online: 25 Jul 2021

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