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OncoImmunology Volume 10, 2021 - Issue 1
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Research Article

Novel adapter CAR-T cell technology for precisely controllable multiplex cancer targeting

Christian M. Seitza Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyORCID Iconhttps://orcid.org/0000-0002-0520-7866View further author information
ORCID Icon,
Joerg Mittelstaetb R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
,
Daniel Atara Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Jana Haua Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Selina Reitera Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Clara Illia Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Verena Kieblea Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Fabian Engertb R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
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Britta Dreesb R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
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Giulia Bendera Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Ann-Christin Krahla Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Philipp Knopfc Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, GermanyView further author information
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Sarah Schroedera Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Nikolas Paulsena Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Alexander Rokhvarguera Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Sophia Scheuermanna Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
,
Elena Rappa Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Anna-Sophia Masta Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Armin Rabsteyna Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, Germany;d Cluster of Excellence iFIT (Exc 2180) “Image-guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, GermanyView further author information
,
Sabine Schleichera Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Stefan Grotea Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Karin Schilbacha Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, GermanyView further author information
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Manfred Kneillingc Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Germany;d Cluster of Excellence iFIT (Exc 2180) “Image-guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, GermanyView further author information
,
Bernd Pichlerc Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Germany;d Cluster of Excellence iFIT (Exc 2180) “Image-guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, GermanyView further author information
,
Dominik Lockb R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
,
Bettina Kotterb R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
,
Sandra Dapab R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
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Stefan Miltenyib R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
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Andrew Kaiserb R&D Department, Miltenyi Biotec GmbH, Bergisch Gladbach, GermanyView further author information
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Peter Langa Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, Germany;d Cluster of Excellence iFIT (Exc 2180) “Image-guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, GermanyView further author information
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Rupert Handgretingera Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, Germany;d Cluster of Excellence iFIT (Exc 2180) “Image-guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, GermanyView further author information
&
Patrick Schlegela Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital Tuebingen, Germany;d Cluster of Excellence iFIT (Exc 2180) “Image-guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, Germany;e School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia;f Cellular Cancer Therapeutics Unit, Children’s Medical Research Institute, Westmead, Australia;g Department of Pediatric Hematology and Oncology, Westmead Children’s Hospital, Westmead, AustraliaCorrespondence[email protected]
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Article: 2003532 | Received 22 Jun 2021, Accepted 03 Nov 2021, Published online: 02 Dec 2021

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