Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Volume 24, 2023 - Issue 5-6
Clinical Trial
COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success
Jeremy M. Shefner1 Barrow Neurological Institute, University of Arizona, and Creighton University, Phoenix, AZ, USACorrespondence[email protected]
https://orcid.org/0000-0001-5067-5602View further author information
https://orcid.org/0000-0001-5067-5602View further author information, Ammar Al-Chalabi2 King’s College London, London, UKhttps://orcid.org/0000-0002-4924-7712View further author information
https://orcid.org/0000-0002-4924-7712View further author information, Jinsy A. Andrews3 The Neurological Institute of New York, Columbia University Irving Medical Center, New York, NY, USAhttps://orcid.org/0000-0002-3474-7140View further author information
https://orcid.org/0000-0002-3474-7140View further author information, Adriano Chio4 Rita Levi Montalcini’ Department of Neuroscience, University of Turin, Turin, Italyhttps://orcid.org/0000-0001-9579-5341View further author information
https://orcid.org/0000-0001-9579-5341View further author information, Mamede De Carvalho5 Department of Neurosciences of Centro Hospitalar Universitário Lisboa-Norte, Faculty of Medicine, Centro de Estudos Egas Moniz, Institute of Molecular Medicine, Universidade de Lisboa, Lisbon, Portugalhttps://orcid.org/0000-0001-7556-0158View further author information
https://orcid.org/0000-0001-7556-0158View further author information, , Philippe Corcia7 Centre de Réference SLA, CHU Bretonneau, Tours, Francehttps://orcid.org/0000-0002-1625-8845View further author information
https://orcid.org/0000-0002-1625-8845View further author information, Philippe Couratier8 Neurology Department, LS Centre CHU Dupuytren, Limoges, Francehttps://orcid.org/0000-0001-9562-856XView further author information
https://orcid.org/0000-0001-9562-856XView further author information, Merit E. Cudkowicz9 Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, MA, USAhttps://orcid.org/0000-0002-7075-1681View further author information
https://orcid.org/0000-0002-7075-1681View further author information, Angela Genge10 Montreal Neurological Institute, Montreal, QC, Canadahttps://orcid.org/0000-0001-5587-9946View further author information
https://orcid.org/0000-0001-5587-9946View further author information, Orla Hardiman11 Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Irelandhttps://orcid.org/0000-0003-2610-1291View further author information
https://orcid.org/0000-0003-2610-1291View further author information, Terry Heiman-Patterson12 Neurology Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USAhttps://orcid.org/0000-0002-9910-1041View further author information
https://orcid.org/0000-0002-9910-1041View further author information, Robert D. Henderson13 UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australiahttps://orcid.org/0000-0002-2820-8183View further author information
https://orcid.org/0000-0002-2820-8183View further author information, Caroline Ingre14 Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Swedenhttps://orcid.org/0000-0001-5327-7204View further author information
https://orcid.org/0000-0001-5327-7204View further author information, Carlayne E. Jackson15 University of Texas Health Science Center at San Antonio, San Antonio, TX, USAhttps://orcid.org/0000-0002-9368-395XView further author information
https://orcid.org/0000-0002-9368-395XView further author information, , Noah Lechtzin17 Johns Hopkins University School of Medicine, Baltimore, MD, USAhttps://orcid.org/0000-0002-9088-8749View further author information
https://orcid.org/0000-0002-9088-8749View further author information, Albert Ludolph18 UULM Clinic of Neurology, Ulm University, Ulm, Germanyhttps://orcid.org/0000-0002-5401-0904View further author information
https://orcid.org/0000-0002-5401-0904View further author information, Nicholas J. Maragakis19 Johns Hopkins ALS Clinical Trials Unit, Johns Hopkins University, Baltimore, MD, USAhttps://orcid.org/0000-0002-7311-9614View further author information
https://orcid.org/0000-0002-7311-9614View further author information, Timothy M. Miller20 Washington University School of Medicine, St. Louis, MO, USAhttps://orcid.org/0000-0002-3424-5511View further author information
https://orcid.org/0000-0002-3424-5511View further author information, Jesus S. Mora Pardina21 ALS Unit, Hospital Universitario San Rafael, Madrid, Spainhttps://orcid.org/0000-0001-6633-5354View further author information
https://orcid.org/0000-0001-6633-5354View further author information, Susanne Petri22 Department of Neurology, Hannover Medical School, Hannover, Germanyhttps://orcid.org/0000-0002-9783-8584View further author information
https://orcid.org/0000-0002-9783-8584View further author information, Zachary Simmons23 Penn State Health Milton S Hershey Medical Center, Hershey, PA, USAhttps://orcid.org/0000-0001-8574-5332View further author information
https://orcid.org/0000-0001-8574-5332View further author information, Leonard H. Van Den Berg24 Department of Neurology, UMC Utrecht Brain Center, Netherlands ALS Centre, University Medical Center Utrecht, Utrecht, Netherlandshttps://orcid.org/0000-0002-5203-9674View further author information
https://orcid.org/0000-0002-5203-9674View further author information, Lorne Zinman25 Sunnybrook Health Sciences Centre, Toronto, ON, Canada, andhttps://orcid.org/0000-0002-8096-8366View further author information
https://orcid.org/0000-0002-8096-8366View further author information, Stuart Kupfer26 Cytokinetics, Incorporated, South San Francisco, CA, USAhttps://orcid.org/0000-0002-5469-1287View further author information
https://orcid.org/0000-0002-5469-1287View further author information, Fady I. Malik26 Cytokinetics, Incorporated, South San Francisco, CA, USAhttps://orcid.org/0000-0002-5597-5759View further author information
https://orcid.org/0000-0002-5597-5759View further author information, , Tyrell J. Simkins26 Cytokinetics, Incorporated, South San Francisco, CA, USAhttps://orcid.org/0000-0002-6063-174XView further author information
https://orcid.org/0000-0002-6063-174XView further author information, , Andrew A. Wolff26 Cytokinetics, Incorporated, South San Francisco, CA, USAhttps://orcid.org/0000-0002-9094-0359View further author information
https://orcid.org/0000-0002-9094-0359View further author information & Stacy A. Rudnicki26 Cytokinetics, Incorporated, South San Francisco, CA, USAhttps://orcid.org/0000-0002-3499-5208View further author information
https://orcid.org/0000-0002-3499-5208View further author information show all