Homologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies

Xun Wanga State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Xiaoyu Zhaoa State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Jieyu Songb Department of Infectious Diseases, Huashan Hospital affiliated with Fudan University, Shanghai, People’s Republic of ChinaView further author information

Jing Wub Department of Infectious Diseases, Huashan Hospital affiliated with Fudan University, Shanghai, People’s Republic of ChinaView further author information

Yuqi Zhuc State Key Laboratory of Genetic Engineering and Engineering Research Center of Gene Technology, Ministry of Education, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Minghui Lia State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Yuchen Cuia State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Yanjia Chena State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Lulu Yanga State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Jun Liuc State Key Laboratory of Genetic Engineering and Engineering Research Center of Gene Technology, Ministry of Education, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, People’s Republic of China;d Fubio (Suzhou) Biomedical Technology Co., Ltd., Suzhou, People’s Republic of ChinaView further author information

Huanzhang Zhuc State Key Laboratory of Genetic Engineering and Engineering Research Center of Gene Technology, Ministry of Education, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Shibo Jiange Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, People’s Republic of ChinaView further author information

Pengfei Wanga State Key Laboratory of Genetic Engineering, Shanghai Institute of Infectious Disease and Biosecurity, School of Life Sciences, Fudan University, Shanghai, People’s Republic of China;c State Key Laboratory of Genetic Engineering and Engineering Research Center of Gene Technology, Ministry of Education, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, People’s Republic of ChinaCorrespondence[email protected]