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Separation Science and Technology Volume 37, 2002 - Issue 7
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Original Articles

High throughput screening and quantitative structure efficacy relationship models for designing displacers for antisense oligonucleotide purification in anion-exchange systems

Nihal Tugcu Chemical Engineering Department, Rensselaer Polytechnic Institute, Troy, NY, 12180, U.S.A.
,
C. B. Mazza Chemical Engineering Department, Rensselaer Polytechnic Institute, Troy, NY, 12180, U.S.A.
,
C. M. Breneman Chemistry Department, Rensselaer Polytechnic Institute, Troy, NY, 12180, U.S.A.
,
Yogesh S. Sanghvi Manufacturing Process Department, 2292 Faraday Avenue, ISIS Pharmaceuticals, Inc., Carlsbad, CA, 92008, U.S.A.
&
S. M. Cramer Chemical Engineering Department, Rensselaer Polytechnic Institute, Troy, NY, 12180, U.S.A.Correspondence[email protected]
Pages 1667-1681 | Published online: 15 Feb 2007

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