Bradykinin B₂ Receptor-Mediated Mitogen-Activated Protein Kinase Activation in COS-7 Cells Requires Dual Signaling via Both Protein Kinase C Pathway and Epidermal Growth Factor Receptor Transactivation

Antje Adomeit1 Institute of Biochemistry and Biophysics, Biological and Pharmaceutical Faculty, Friedrich Schiller University, D-07743Jena

Angela Graness1 Institute of Biochemistry and Biophysics, Biological and Pharmaceutical Faculty, Friedrich Schiller University, D-07743Jena

Steffen Gross2 Research Group “Molecular Cell Biology,” Medical Faculty, Friedrich Schiller University, D-07747Jena, Germany

Klaus Seedorf3 Hagedorn Research Institute, Department of Molecular Signaling, 2820Gentofte, Denmark

Reinhard Wetzker2 Research Group “Molecular Cell Biology,” Medical Faculty, Friedrich Schiller University, D-07747Jena, Germany

Claus Liebmann1 Institute of Biochemistry and Biophysics, Biological and Pharmaceutical Faculty, Friedrich Schiller University, D-07743JenaCorrespondence[email protected]

Bradykinin B₂ Receptor-Mediated Mitogen-Activated Protein Kinase Activation in COS-7 Cells Requires Dual Signaling via Both Protein Kinase C Pathway and Epidermal Growth Factor Receptor Transactivation

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Bradykinin B2 Receptor-Mediated Mitogen-Activated Protein Kinase Activation in COS-7 Cells Requires Dual Signaling via Both Protein Kinase C Pathway and Epidermal Growth Factor Receptor Transactivation

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Bradykinin B₂ Receptor-Mediated Mitogen-Activated Protein Kinase Activation in COS-7 Cells Requires Dual Signaling via Both Protein Kinase C Pathway and Epidermal Growth Factor Receptor Transactivation