Cancer Management and Research
Volume 3, 2011 - Issue
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Original Research
Dose study of the multikinase inhibitor, LY2457546, in patients with relapsed acute myeloid leukemia to assess safety, pharmacokinetics, and pharmacodynamics
Volker Wacheck1 Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;
, Michael Lahn2 Early Oncology Clinical Investigation, Eli Lilly and Company, Indianapolis, IN, USA;
, Gemma Dickinson3 Department of Pharmacokinetics, Eli Lilly and Company, Erl Wood Research Centre, Windlesham, Surrey, UK;
, Wolfgang Füreder4 Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;
, Renata Meyer4 Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;
, Susanne Herndlhofer4 Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;
, Thorsten Füreder1 Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;
, Georg Dorfner5 Eli Lilly GesmbH, Medical Department, Vienna, Austria;
, Sada Pillay2 Early Oncology Clinical Investigation, Eli Lilly and Company, Indianapolis, IN, USA;
, Valérie André6 Department of Statistics, Eli Lilly and Company, Erl Wood Research Centre, Surrey, UK;
, Timothy P Burkholder7 Discovery Chemistry Research and Technology, Eli Lilly and Company, Indianapolis, IN, USA;
, Jacqueline K Akunda8 Nonclinical Toxicology, Eli Lilly and Company, Indianapolis, IN, USA;
, Leann Flye-Blakemore9 Flow Cytometry and Cell Analysis, Esoterix Clinical Trials Services, Mechelen, Belgium;
, Dirk Van Bockstaele9 Flow Cytometry and Cell Analysis, Esoterix Clinical Trials Services, Mechelen, Belgium;
, Richard F Schlenk10 Universitätsklinikum Ulm, Klinik für Innere Medizin III, Ulm, Germany;
, Wolfgang R Sperr4 Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;
& Peter Valent4 Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel, Vienna, Austria;;11 Ludwig Boltzmann Cluster Oncology, Vienna, AustriaCorrespondence[email protected]
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Pages 157-175
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Published online: 30 Sep 2022
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