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Drug Design, Development and Therapy Volume 14, 2020 - Issue
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Original Research

Metabolic Activation and Covalent Protein Binding of Berberrubine: Insight into the Underlying Mechanism Related to Its Hepatotoxicity

Kai Wang1 School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, People’s Republic of China
,
Jinqiu Rao1 School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, People’s Republic of China
,
Tingting Zhang1 School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, People’s Republic of China
,
Qing Gao2 School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, People’s Republic of China
,
Jichao Zhang3 State Key Laboratory of Component-based Chinese Medicine,Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China
,
Chenxi Guang3 State Key Laboratory of Component-based Chinese Medicine,Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China
,
Liqin Ding3 State Key Laboratory of Component-based Chinese Medicine,Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China
&
Feng Qiu1 School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, People’s Republic of China;3 State Key Laboratory of Component-based Chinese Medicine,Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of ChinaCorrespondence[email protected]
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Pages 4423-4438 | Published online: 22 Oct 2020

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