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Original Research
New structure–activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity
Luciana Pereira Rangel1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France;2 Department of General Microbiology, Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
, Evelyn Winter1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France;3 Department of Pharmaceutical Sciences, PPGFAR, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
, Charlotte Gauthier1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France
, Raphaël Terreux4 Equipe BISI, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France
, Louise D Chiaradia-Delatorre5 Department of Chemistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
, Alessandra Mascarello5 Department of Chemistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
, Ricardo J Nunes5 Department of Chemistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
, Rosendo A Yunes5 Department of Chemistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
, Tania B Creczynski-Pasa3 Department of Pharmaceutical Sciences, PPGFAR, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
, Sira Macalou1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France
, Doriane Lorendeau1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France
, Hélène Baubichon-Cortay1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, France
, Antonio Ferreira-Pereira2 Department of General Microbiology, Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
& Attilio Di Pietro1 Equipe Labellisée Ligue 2013, BMSSI UMR 5086 CNRS/Université Lyon 1, Institut de Biologie et Chimie des Protéines, Lyon, FranceCorrespondence[email protected]
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Pages 1043-1052
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Published online: 30 Sep 2013
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