Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment

Dandan Wang1 Department of Pathology, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;

Xiaowei Xu2 Department of Periodontology, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;

Kai Zhang3 State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, People’s Republic of China;

Bin Sun4 Department of Oral and Maxilloficial Syrgery, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;

Lu Wang1 Department of Pathology, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;

Lin Meng1 Department of Pathology, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;

Qilin Liu4 Department of Oral and Maxilloficial Syrgery, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;

Changyu Zheng5 Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA;

Bai Yang3 State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, People’s Republic of China;

Hongchen Sun1 Department of Pathology, School and Hospital of Stomatology, Jilin University, Changchun, People’s Republic of China;;3 State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, People’s Republic of China;;6 Key Laboratory of Science and Technology for Stomatology Nanoengineering, The Education Department of Jilin Province, Changchun, People’s Republic of ChinaCorrespondence[email protected]

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Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment

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Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment

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