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Original Research
Verteporfin-Loaded Anisotropic Poly(Beta-Amino Ester)-Based Micelles Demonstrate Brain Cancer-Selective Cytotoxicity and Enhanced Pharmacokinetics
James G Shamul1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA
, Sagar R Shah1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;3 Department of Neurosurgery, Mayo Clinic, Jacksonville, FL32224, USA
, Jayoung Kim1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA
, Paula Schiapparelli3 Department of Neurosurgery, Mayo Clinic, Jacksonville, FL32224, USA
, Carla A Vazquez-Ramos3 Department of Neurosurgery, Mayo Clinic, Jacksonville, FL32224, USA
, Ben J Lee1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA
https://orcid.org/0000-0002-9395-318X
Kisha K Patel1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA
, Alyssa Shin1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA
https://orcid.org/0000-0001-8505-9252
Alfredo Quinones-Hinojosa3 Department of Neurosurgery, Mayo Clinic, Jacksonville, FL32224, USACorrespondence[email protected] [email protected]
& Jordan J Green1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;2 Translational Tissue Engineering Center and Institute for NanoBioTechnology, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;4 Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD21231, USA;5 Department of Oncology, The Sidney Kimmel Comprehensive Cancer, and The Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD21231, USA;6 Department of Ophthalmology, Department of Materials Science and Engineering, and Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD21231, USA
https://orcid.org/0000-0003-4176-3808
Pages 10047-10060
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Published online: 23 Dec 2019
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