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Original Research
Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol
Vanessa Fontana1 The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK;2 MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UKCorrespondence[email protected]
https://orcid.org/0000-0002-0146-9113
Richard Myles Turner1 The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK;2 MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
, Ben Francis3 Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, Liverpool, UK
, Peng Yin3 Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, Liverpool, UK
, Benno Pütz4 Max Planck Institute of Psychiatry, Munich, Germany
https://orcid.org/0000-0002-2208-209X
Timo P Hiltunen5 Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland
https://orcid.org/0000-0001-7011-0422
Sanni Ruotsalainen6 Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, Finland
, Kimmo K Kontula5 Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland
, Bertam Müller-Myhsok1 The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK;4 Max Planck Institute of Psychiatry, Munich, Germany
& Munir Pirmohamed1 The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK;2 MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK;7 Royal Liverpool and Broadgreen University Hospitals NHS Trust, and Liverpool Health Partners, Liverpool, UK
https://orcid.org/0000-0002-7534-7266
Pages 249-260
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Published online: 22 Mar 2022
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