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Epigenomics Volume 13, 2021 - Issue 17
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Research Article

Methylation of TMEM176A, a key ERK Signaling Regulator, is a Novel Synthetic Lethality Marker of ATM Inhibitors in Human Lung Cancer

Hongxia Li1 Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;2 Faculty of Environmental & Life Science, Beijing Key Laboratory of Environmental & Oncology, Beijing University of Technology, Beijing, 100124, ChinaView further author information
,
Weili Yang1 Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, ChinaView further author information
,
Meiying Zhang1 Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, ChinaView further author information
,
Tao He3 Department of Pathology, Characteristic Medical Center of The Chinese People’s Armed Police Force, Tianjin, 300162, ChinaView further author information
,
Fuyou Zhou4 Department of Thoracic Surgery, Anyang Tumor Hospital, Anyang, 455000, Henan, ChinaView further author information
,
James G Herman5 The Hillman Cancer Center, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Suite 2.18/Research, Pittsburgh, PA15213, USAView further author information
,
Liming Hu2 Faculty of Environmental & Life Science, Beijing Key Laboratory of Environmental & Oncology, Beijing University of Technology, Beijing, 100124, ChinaView further author information
&
Mingzhou Guo1 Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China;6 Henan Key Laboratory for Esophageal Cancer Research, Zhengzhou University, 40 Daxue Road, Zhengzhou, Henan, 450052, China;7 State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, #28 Fuxing Road, Beijing, 100853, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9445-9984View further author information
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Pages 1403-1419 | Received 20 Jun 2021, Accepted 07 Sep 2021, Published online: 24 Sep 2021

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