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Pharmacogenomics Volume 17, 2016 - Issue 15
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Research Article

Moving Toward Personalized Medicine in Rheumatoid Arthritis: Snps in Methotrexate Intracellular Pathways are Associated with Methotrexate Therapeutic Outcome

Aurea Lima1 CESPU, Institute of Research & Advanced Training in Health Sciences & Technologies, Department of Pharmaceutical Sciences, Rua Central de Gandra 1317, 4585-116GandraPRD, Portugal;2 Molecular Oncology & Viral Pathology Group – Research Center, Portuguese Institute of Oncology of Porto (IPO-Porto), Rua Dr. António Bernardino de Almeida, 4200-072Porto, Portugal;3 Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313Porto, PortugalCorrespondence[email protected]
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,
Miguel Bernardes4 Faculty of Medicine of University of Porto (FMUP), Al. Prof. Hernâni Monteiro, 4200-319Porto, Portugal;5 Rheumatology Department of São João Hospital Center, Al. Prof. Hernâni Monteiro, 4200-319 Porto, PortugalView further author information
,
Rita Azevedo3 Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313Porto, Portugal;6 Experimental Pathology & Therapeutics Group – Research Center, Portuguese Institute of Oncology of Porto (IPO-Porto), Rua Dr. António Bernardino de Almeida, 4200-072Porto, PortugalView further author information
,
Vitor Seabra1 CESPU, Institute of Research & Advanced Training in Health Sciences & Technologies, Department of Pharmaceutical Sciences, Rua Central de Gandra 1317, 4585-116GandraPRD, PortugalView further author information
&
Rui Medeiros2 Molecular Oncology & Viral Pathology Group – Research Center, Portuguese Institute of Oncology of Porto (IPO-Porto), Rua Dr. António Bernardino de Almeida, 4200-072Porto, Portugal;3 Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313Porto, Portugal;7 Research Department-Portuguese League Against Cancer (LPCC-NRNorte), Estrada Interior da Circunvalação, 6657, 4200-177Porto, PortugalView further author information
Pages 1649-1674 | Received 13 Apr 2016, Accepted 13 Apr 2016, Published online: 27 Sep 2016

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