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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 7
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General Xenobiochemistry

The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes

Katharine HoweFaculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey
,
Faizah SanatFaculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey
,
Alfred E. ThumserFaculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Surrey
,
Tanya ColemanClinical Pharmacology and DMPK, AstraZeneca, Macclesfield, Cheshire
&
Nick PlantFaculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, SurreyCorrespondence[email protected]
Pages 519-529 | Received 11 Jan 2011, Accepted 04 Mar 2011, Published online: 09 Apr 2011

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