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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 12
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General Xenobiochemistry

Using human recombinant UDP-glucuronosyltransferase isoforms and a relative activity factor approach to model total body clearance of laropiprant (MK-0524) in humans

Christopher R. GibsonPharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM), Merck Research Laboratories West Point, PA (CRG, PL, CM, CW, MS) and Rahway, NJ (DNG)USACorrespondence[email protected]
,
Ping LuPharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM), Merck Research Laboratories West Point, PA (CRG, PL, CM, CW, MS) and Rahway, NJ (DNG)USA
,
Cheri MaciolekPharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM), Merck Research Laboratories West Point, PA (CRG, PL, CM, CW, MS) and Rahway, NJ (DNG)USA
,
Christen WudarskiPharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM), Merck Research Laboratories West Point, PA (CRG, PL, CM, CW, MS) and Rahway, NJ (DNG)USA
,
Zoe BarterSimCYP Ltd. (now Certara) SheffieldUK
,
Karen Rowland-YeoSimCYP Ltd. (now Certara) SheffieldUK
,
Mark StrohPharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM), Merck Research Laboratories West Point, PA (CRG, PL, CM, CW, MS) and Rahway, NJ (DNG)USA
,
Eseng LaiDepartment of Clinical Pharmacology, Merck Research Laboratories Rahway, NJUSA
&
Deborah A. Nicoll-GriffithPharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM), Merck Research Laboratories West Point, PA (CRG, PL, CM, CW, MS) and Rahway, NJ (DNG)USA
 show all
Pages 1027-1036 | Received 22 Jan 2013, Accepted 28 Mar 2013, Published online: 03 May 2013

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