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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 4
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Clinical Pharmacokinetics and Metabolism

Trametinib, a first-in-class oral MEK inhibitor mass balance study with limited enrollment of two male subjects with advanced cancers

May Y. K. HoDrug Metabolism and Pharmacokinetics, GlaxoSmithKline King of Prussia, PAUSACorrespondence[email protected]
,
Michael J. MorrisDrug Metabolism and Pharmacokinetics, GlaxoSmithKline King of Prussia, PAUSA
,
Jill L. PirhallaDrug Metabolism and Pharmacokinetics, GlaxoSmithKline King of Prussia, PAUSA
,
John W. BaumanOncology Research and Development, GlaxoSmithKline, Research Triangle Park Durham, NCUSA
,
Carolyn B. PendryOncology Research and Development, GlaxoSmithKline, Research Triangle Park Durham, NCUSA
,
Keith W. OrfordCombination Therapies Unit, GlaxoSmithKline Upper Providence, PAUSA
,
Royce A. MorrisonComprehensive Clinical Development Tacoma, WAUSA
&
Donna S. CoxClinical Pharmacology Modeling and Simulation, GlaxoSmithKline King of Prussia, PAUSA
 show all
Pages 352-368 | Received 06 Jun 2013, Accepted 30 Jul 2013, Published online: 23 Aug 2013

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