Decreased exposure of atorvastatin in diabetic rats partly due to induction of hepatic Cyp3a and Oatp2

Nan ShuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Mengyue HuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Can LiuDepartment of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, USA, and

Mian ZhangCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Zhaoli LingCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Ji ZhangDepartment of Pharmacy, the First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, China

Ping XuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Zeyu ZhongCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Yang ChenCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China,

Li LiuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China, Correspondence[email protected] [email protected]

Xiaodong LiuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China, Correspondence[email protected] [email protected]

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