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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 2
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Original Article

Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: Analysis of interspecies variability and comparison with metabolism in vivo

G. W. Sandker Department of Pharmacology and Therapeutics, University Centre for Pharmacy, Anthonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands
,
R. M. E. Vos Akzo Pharma Organon International BV, PO Box 20, 5340 BH, Oss, The Netherlands
,
L. P. C. Delbressine Akzo Pharma Organon International BV, PO Box 20, 5340 BH, Oss, The Netherlands
,
M. J. H. Slooff Department of Surgery, University Hospital, Oostersingel 59, 9713 EZ, Groningen, The Netherlands
,
D. K. F. Meijer Department of Pharmacology and Therapeutics, University Centre for Pharmacy, Anthonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands
&
G. M. M. Groothuis Department of Pharmacology and Therapeutics, University Centre for Pharmacy, Anthonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands
Pages 143-155 | Received 05 Aug 1993, Published online: 27 Aug 2009

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