Effect of alginate microencapsulation on the catalytic efficiency and in vitro enzyme-prodrug therapeutic efficacy of cytosine deaminase and of recombinant E. coli expressing cytosine deaminase

Michael G. FunaroDartmouth College, Hanover, NH, USA;

Krishnamurthy V. NemaniDepartment of Radiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA;

Zhihang ChenDivision of Cancer Imaging Research, Johns Hopkins University ICMIC Program, Russell H. Morgan Department of Radiology and Radiological Science, the Johns Hopkins University School of Medicine, Baltimore, MD, USA;

Zaver M. BhujwallaDivision of Cancer Imaging Research, Johns Hopkins University ICMIC Program, Russell H. Morgan Department of Radiology and Radiological Science, the Johns Hopkins University School of Medicine, Baltimore, MD, USA;

Karl E. GriswoldThayer School of Engineering at Dartmouth, Hanover, NH, USA;

Barjor GimiDepartment of Radiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA; ;Thayer School of Engineering at Dartmouth, Hanover, NH, USA; ;Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH, USACorrespondence[email protected]

Effect of alginate microencapsulation on the catalytic efficiency and in vitro enzyme-prodrug therapeutic efficacy of cytosine deaminase and of recombinant E. coli expressing cytosine deaminase

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Effect of alginate microencapsulation on the catalytic efficiency and in vitro enzyme-prodrug therapeutic efficacy of cytosine deaminase and of recombinant E. coli expressing cytosine deaminase

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